Mortality Of Pancreatic Cancer And Pancreatic Clinical Trials

Mortality of pancreatic cancer is the fifth highest mortality rate of all cancer related diseases in the United States today. On the basis of pancreatic cancer stages, cancer of the pancreas has the shortest average survival time compared with all other cancer types.

Mortality of pancreatic cancer is probably linked to the fact that the pancreas serves numerous vital functions. There are two main cancers of the pancreas namely exocrine and endocrine types. Pancreatic cancer mortality rate is higher with exocrine type cancer. The exocrine in the pancreas produces several enzymes, which are taken straight into the small intestine to aid in the digestion of food.

The endocrine is made up of clusters of cells within the pancreas. These are known as pancreatic islet cell(s) or the islets of Langerhans. These produce several different hormones including glucagons and insulin. One pancreatic cancer treatment involves removing the pancreatic islet cell from a deceased donor, purifying, processing, and transplanting them. Mortality of pancreatic cancer in the endocrine type is also lower because it grows much slower.

Pancreatic cancer cells may spread by direct extension from the pancreas to adjacent structures, for example colon, spleen, adrenal glands, kidneys, small intestine bile duct, or vertebra. The most usual sites of distant spread include the lungs and liver and in these cases, spread is via the bloodstream. The highest mortality of pancreatic cancer occurs in advanced pancreatic cancer. In pancreatic cancer stages, this is classified as stage 1V and it is inoperable. This is where the cancer has spread and may have formed lung or liver cancer.

Two closely associated diseases, which have been the subject of multiple studies, are diabetes and pancreatitis, although so far, there have been conflicting results and these are usually regarded as pancreatic cancer symptoms.

With the mortality of pancreatic cancer being so high, it makes good sense to look at and review our lifestyles. This is because many pancreatic cancer causes are linked to smoking, drinking too much and a diet high in fats and low in fiber.

Any one suffering from this disease can opt to participate in pancreatic cancer clinical trials. These are research studies that are planned to experiment with new treatments on humans. They include chemotherapy, different methods of managing radiation therapy, nutritional therapies, behavioral therapies, immunologic agents, and medical devices. Taking part in pancreatic cancer clinical trials is not being a "guinea pig." These trials are designed carefully and undergo strict reviews and controls by the FDA.

It is important to remember that any pancreatic cancer mortality figures for five years mortality only considers individuals who were diagnosed over five years ago. Since then, there have been significant advances in all areas of pancreatic cancer treatments. Consequently, pancreatic cancer survival rates are probably considerably higher than what they were five years ago.